Rapid Determination of Fentanyl-kind Analogs and Their Mass Fragmentation Routes by High Resolution Mass Spectrometry
To develop an approach of coupling liquid chromatography with Q-Exactive high resolution mass spectrometry (HRMS) for determination of 25 fentanyl-kind analogs and 2 precursors so that both the fragmentation pathways and characteristic ions of such fentanyl-kind analogs were to analyze for providing a reference into the identification of suspected fentanyl-kind chemicals without standards, meanwhile presenting a foundation for new psychoactive substances to be supervised timely or as early as possible. The fentanyl-kind solid drugs were extracted with methanol under ultrasound, and those li
